Awarded second place in the 2018 AJN Book of the Year Award in the Advanced Practice Nursing category Awarded third place in the 2018 AJN Book of the Year Award in the Maternal-Child Health/Prenatal Nursing/Childbirth category Complex concepts made manageable! Build the foundation you need to understand the science of genetics and its growing role in the diagnosis and treatment of diseases and disorders. Confidently tackle the basics of genetic inheritance, the influence of somatic and germline mutations, the multifactorial relationship of gene-environment interactions, and the foundation of ethical behavior. Everyday language makes these often-intimidating topics easy to understand, while clearly defined principles, logical explanations, illustrations, tables, and clinical examples ensure you master the material. See what students are saying online about the previous edition... Genetics simplified and easy to understand. "Genetics simplified and easy to understand. Wish I had this when learning DNA replication in Microbiology. Lot of good charts. I plan to keep even after the class because it's interesting and easy to understand." - Katalina Cade Great resource! "This is a complex subject and this book makes it so much easier to learn and understand! I love the "memory hints" it gives you throughout the book." - Kira Short
Professor Emerita, University of Cincinnati, Cincinnati, Ohio Author and Consultant, Cincinnati, Ohio Formerly the Mary Cox Professor and Coordinator of the Healthcare Genetics Doctoral Program, Clemson university School of Nursing, Clemson, South Carolina
I. Basic Concepts from Molecular Genetics 1. DNA Structure and Function 2. Protein Synthesis 3. Genetic Influences on Cell Division, Cell Differentiation, and Gametogenesis II. Gene Expression 4. Patterns of Inheritance 5. Epigenetic Influences on Gene Expression (NEW) 6. Autosomal Inheritance and Disorders (NEW) 7. Sex Chromosome and Mitochondrial Inheritance and Disorders 8. Family History and Pedigree Construction 9. Congenital Anomalies, Basic Dysmorphology, and Genetic Assessment III. Genomic Health Problems Across the Life Span 10. Enzyme and Collagen Disorders 11. Common Childhood-Onset Genetic Disorders 12. Common Adult-Onset Genetic Disorders IV. Genomic Influences on Selected Common Health Problems 13. Cardiovascular Disorders 14. The Genetics of Cancer 15. Genetic Contributions to Psychiatric and Behavioral Disorders V. Genomics and Disease Management 16. Genetic and Genomic Testing 17. Assessing Genomic Variation in Drug Response 18. Health Professionals and Genomic Care VI. Global Genomic Issues 19. Financial, Ethical, Legal, and Social Considerations 20. Genetic and Genomic Variation Appendices A. Genetic Organizations and Support Groups B. Selected Educational Websites Glossary
